
This Mediterranean Chicken Zucchini Bake is a weeknight lifesaver for anyone craving something healthy and packed with sun-drenched flavors. It is a cheesy one-pan masterpiece that comes together quickly with tender chicken and lots of fresh vegetables which always makes me think of summer at the beach. Whenever I want an easy meal that still feels nourishing and impressive this is the recipe I reach for.
My partner doubted a zucchini casserole would ever beat takeout but now it is a regular rotation saver for our busiest weeknights.
Ingredients
- Boneless skinless chicken breasts: choose plump pieces for juicy bites and slice evenly for even cooking
- Zucchini: brings moisture and subtle sweetness smaller ones are best for tenderness
- Cherry tomatoes: offer a burst of flavor look for deeply colored and glossy fruit
- Red onion: lends color and gentle bite pick ones that feel heavy for their size
- Garlic: adds savor and depth crush fresh cloves for full aroma
- Olive oil: for richness choose extra virgin for best flavor
- Dried oregano and basil: key for classic Mediterranean notes dried herbs here keep it convenient
- Smoked paprika: gives smoky warmth look for a deep red variety
- Salt and black pepper: season throughout for balanced flavor
- Red pepper flakes: offer a little heat use them if you like things spicy
- Shredded mozzarella cheese: for melt factor whole milk mozzarella is creamier
- Parmesan cheese: for salty sharp top layer always grate fresh if possible
- Fresh parsley: as a finishing touch adds brightness and color flat leaf parsley works best
Step-by-Step Instructions
- Preheat and Prepare:
- Set your oven to 375 degrees Fahrenheit or 190 degrees Celsius for reliable roasting. Take a small moment to lightly grease a nine by thirteen inch baking dish with olive oil so nothing sticks. This step sets you up for happy cleanup later.
- Season the Chicken and Vegetables:
- Combine your chicken cubes zucchini slices halved cherry tomatoes slivered red onion and minced garlic in a generous bowl. Pour in olive oil then tumble in oregano basil smoked paprika salt pepper and red pepper flakes if using. Toss together with your hands or a sturdy spoon so every piece glistens with seasoning.
- Assemble the Bake:
- Pour the seasoned chicken and veggie mixture into the prepared baking dish. Spread everything in an even layer so the pieces touch but are not crowded. Scatter shredded mozzarella and parmesan evenly over the top for a golden cheesy crust.
- Bake the Dish:
- Cover the dish with foil to capture moisture and set in the oven for twenty minutes. After this remove the foil carefully to avoid steam and let bake another ten to fifteen minutes until the cheese is golden bubbly and your chicken registers one sixty five degrees Fahrenheit internally. This final bake allows everything to meld together beautifully.
- Serve and Enjoy:
- Let it sit a few minutes once out of the oven so the juices settle. A sprinkle of chopped fresh parsley goes on just before scooping onto plates. Serve warm with fluffy rice tangy quinoa or a thick slice of crusty bread to soak up everything.

The cherry tomatoes are my not so secret favorite since they roast into little jewels of flavor that pop in every bite. I always think of my childhood backyard garden whenever I taste them in this bake.
Storage Tips
Store leftovers in an airtight container in the fridge for three days. Reheat gently in the oven or microwave with a splash of water if needed to prevent the chicken from drying out. The vegetables keep their texture best if reheated slowly rather than at high temp.
Ingredient Substitutions
Try boneless chicken thighs for an even juicier result or swap in yellow squash for zucchini when you want more color. If you are dairy free use plant based mozzarella and omit parmesan. Sun dried tomatoes can be added for even deeper flavor if fresh tomatoes are hard to find.

Serving Suggestions
This bake is delicious as the main event. Round out your meal with herbed rice a lemony orzo salad or a simple green salad with olives. For a heartier table serve alongside roasted potatoes or a creamy tzatziki dip.
Cultural Context
Mediterranean casseroles like this are common for family dinners across Southern Europe. Each region has its own spin some using eggplant or different cheeses. This version is a simple bridge between Greek and Italian home cooking making it as adaptable as it is flavorful.
Recipe FAQs
- → What is the best way to keep the chicken tender?
Ensure the chicken pieces are cut uniformly and avoid overbaking. Bake just until the chicken reaches 165°F for juicy results.
- → Can I use feta cheese instead of mozzarella?
Yes, feta adds classic Mediterranean flair and a touch of tanginess. You can use it alone or alongside mozzarella for extra creaminess.
- → Is it possible to prepare this dish ahead of time?
Absolutely! You can assemble the chicken and vegetables in the baking dish, cover, and refrigerate for a few hours before baking.
- → What side dishes pair well with this bake?
This dish goes wonderfully with rice, quinoa, or fresh crusty bread. A simple green salad is another great complement.
- → How do I add more heat to the dish?
Sprinkle in a bit more red pepper flakes or add a dash of cayenne if you prefer a spicy Mediterranean twist.